Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.61 |
| ▸ | AURKA | O14965 | 1/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | CASP6 | P55212 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28065855 | 0.87 | TTR (0.61) | TTRAURKAAURKBALDH1A1CASP6 | |
| SCHEMBL5442629 | 0.85 | TTR (0.48) | TTRAURKAAURKBALDH1A1HSD17B10 | |
| SCHEMBL6051270 | 0.82 | TTR (0.59) | TTRAURKAAURKBALDH1A1CASP6 | |
| SCHEMBL9331048 | 0.79 | AURKA (0.53) | TTRAURKAAURKBALDH1A1CASP6 | |
| SCHEMBL10712705 | 0.79 | ALDH1A1 (0.50) | TTRALDH1A1CASP6HSD17B10CYP2C9 | |
| SCHEMBL600908 | 0.79 | TTR (0.59) | TTRAURKAAURKBALDH1A1CASP6 | |
| SCHEMBL7890129 | 0.78 | TTR (0.48) | TTRAURKAAURKBHSD17B10KDM4E | |
| SCHEMBL2904202 | 0.78 | TTR (0.48) | TTRAURKAAURKBALDH1A1HSD17B10 | |
| SCHEMBL31255668 | 0.78 | TTR (0.48) | TTRAURKAAURKBHSD17B10KDM4E | |
| SCHEMBL14645562 | 0.78 | CASP6 (0.63) | TTRAURKAAURKBALDH1A1CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013008201-A2 | NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF | COLOURTEX INDUSTRIES LIMITED (IN) | 2013-01-17 | — | — | WO | claimed |
| WO-2013008201-A2 | NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF | COLOURTEX INDUSTRIES LIMITED (IN) | 2013-01-17 | — | — | WO | disclosed |