Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.44 |
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 5/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1164781 | 1.00 | GSK3B (0.56) | GSK3BCA2PLA2G4AGPR35CES2 | |
| SCHEMBL12374319 | 1.00 | GSK3B (0.56) | GSK3BCA2PLA2G4AGPR35CES2 | |
| SCHEMBL14645639 | 1.00 | GSK3B (0.56) | GSK3BCA2PLA2G4AGPR35CES2 | |
| SCHEMBL1156737 | 0.84 | CA2 (0.45) | GSK3BCA2PLA2G4AGPR35HSD17B3 | |
| SCHEMBL1157000 | 0.83 | GPR35 (0.55) | CA2PLA2G4AGPR35HSD17B3FFAR1 | |
| SCHEMBL10144491 | 0.81 | GPR35 (0.57) | CA2PLA2G4AGPR35CES2CES1 | |
| SCHEMBL1365090 | 0.79 | CES2 (0.47) | PLA2G4AGPR35CES2CES1HSD17B3 | |
| SCHEMBL1363701 | 0.79 | CES2 (0.47) | PLA2G4AGPR35CES2CES1HSD17B3 | |
| SCHEMBL1364678 | 0.79 | CES2 (0.47) | PLA2G4AGPR35CES2CES1HSD17B3 | |
| SCHEMBL1156997 | 0.79 | POLB (0.46) | CA2PLA2G4AGPR35HSD17B3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| US-20140131628-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2014-05-15 | — | — | US | disclosed |
| EP-2729513-A2 | CONJUGATED POLYMERS | Merck Patent GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007334-A2 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |
| WO-2013007334-A2 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |