Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | POLA1 | P09884 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.32 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.32 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | POLG | P54098 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8904751 | 0.75 | FGFR1 (0.43) | FGFR1SLC22A6POLA1POLBPOLG | |
| SCHEMBL8677038 | 0.72 | FGFR1 (0.41) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL8904777 | 0.71 | FGFR1 (0.52) | FGFR1SLC22A6POLA1 | |
| SCHEMBL10047082 | 0.70 | LMNA (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL5280050 | 0.68 | FGFR1 (0.57) | FGFR1SLC22A6POLA1POLBPOLG | |
| SCHEMBL22779512 | 0.68 | LMNA (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL22399931 | 0.68 | LMNA (0.35) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL21099698 | 0.68 | FGFR1 (0.38) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL25585870 | 0.68 | FGFR1 (0.36) | FGFR1SLC22A6LMNATHRBMTOR | |
| SCHEMBL23171293 | 0.67 | FGFR1 (0.35) | FGFR1SLC22A6LMNATHRBMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729153-A1 | CONDENSED PYRIMIDINE NUCLEOSIDE ANALOGS AS ANTI -VIRAL AGENTS | University College Cardiff Consultants, Ltd. (GB) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007992-A1 | CONDENSED PYRIMIDINE NUCLEOSIDE ANALOGS AS ANTI -VIRAL AGENTS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2013-01-17 | — | — | WO | disclosed |