Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | HPRT1 | P00492 | 3/20 | 0.32 |
| ▸ | POLA1 | P09884 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | POLG | P54098 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645666 | 0.75 | FGFR1 (0.48) | FGFR1SLC22A6POLA1POLBPOLG | |
| Ammonia Solution, Strong SCHEMBL9126268 | 0.73 | FGFR1 (0.48) | FGFR1SLC22A6PNPHPRT1POLA1 | |
| Ammonia Solution, Strong SCHEMBL9126284 | 0.73 | FGFR1 (0.48) | FGFR1SLC22A6PNPHPRT1POLA1 | |
| SCHEMBL8896100 | 0.73 | FGFR1 (0.57) | FGFR1SLC22A6PNPHPRT1 | |
| SCHEMBL8714133 | 0.72 | FGFR1 (0.56) | FGFR1SLC22A6PNPHPRT1 | |
| SCHEMBL8711315 | 0.71 | FGFR1 (0.46) | FGFR1SLC22A6POLA1 | |
| SCHEMBL8904777 | 0.71 | FGFR1 (0.52) | FGFR1SLC22A6POLA1 | |
| SCHEMBL6268982 | 0.70 | LMNA (0.37) | FGFR1SLC22A6 | |
| SCHEMBL4711405 | 0.69 | FGFR1 (0.58) | FGFR1SLC22A6PNPHPRT1POLA1 | |
| SCHEMBL22399931 | 0.68 | LMNA (0.35) | FGFR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0398231-B1 | Nucleoside analogs | ACAD OF SCIENCE CZECH REPUBLIC (CZ) | 1997-07-16 | — | — | EP | disclosed |
| EP-0398231-A2 | Nucleoside analogs | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-11-22 | — | — | EP | disclosed |