Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14645740 | 0.99 | ALDH1A1 (0.53) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15733308 | 0.93 | ALDH1A1 (0.44) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL15733058 | 0.88 | CYP2D6 (0.41) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL11132937 | 0.86 | ALDH1A1 (0.55) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL12326380 | 0.85 | ALDH1A1 (0.47) | TSHRCYP3A4MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL15733163 | 0.83 | TSHR (0.49) | TSHRTP53ALDH1A1KDM4EPOLB | |
| SCHEMBL14645956 | 0.80 | ALDH1A1 (0.48) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL14645787 | 0.80 | ALDH1A1 (0.57) | TSHRCYP3A4MAPK1ALDH1A1HSD17B10 | |
| SCHEMBL8134965 | 0.80 | ALDH1A1 (0.55) | TSHRTP53CYP3A4MAPK1ALDH1A1 | |
| SCHEMBL14645996 | 0.79 | ALDH1A1 (0.50) | TSHRTP53CYP3A4MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729444-B1 | METHOD FOR MANUFACTURING 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER IP GMBH (DE) | 2017-08-23 | — | — | EP | disclosed |
| US-9169198-B2 | Method for the production of 2-amino-5-cyano-N,3-dimethylbenzamide | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-10-27 | — | — | US | disclosed |
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-05-29 | — | — | US | disclosed |
| EP-2729444-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | Bayer Intellectual Property GmbH (DE) | 2014-05-14 | — | — | EP | disclosed |
| WO-2013007603-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148611-A1 | METHOD FOR THE PRODUCTION OF 2-AMINO-5-CYANO-N,3-DIMETHYLBENZAMIDE | ALKBH5, ALKBH2, MMAB | TSHR 4356/4885TP53 4239/4885CYP3A4 438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.