Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.32 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CASP1 | P29466 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11136521 | 0.89 | THRB (0.32) | THRBP2RX2ALDH1A1KDM4EMAPT | |
| SCHEMBL14271164 | 0.84 | P2RX5 (0.37) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14546771 | 0.84 | P2RX5 (0.37) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14546744 | 0.82 | P2RX5 (0.38) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14546970 | 0.81 | PHLPP2 (0.37) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14683452 | 0.81 | TDP1 (0.36) | THRBALDH1A1TDP1HTT | |
| SCHEMBL13892263 | 0.80 | NSD2 (0.48) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL2483843 | 0.79 | BRD4 (0.37) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14546781 | 0.79 | ENPP2 (0.43) | THRBP2RX5P2RX4P2RX2ENPP1 | |
| SCHEMBL14546749 | 0.79 | TDP1 (0.36) | THRBP2RX5P2RX4P2RX2ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013008201-A2 | NOVEL REACTIVE DYES, THERE MIXTURES AND PROCESSES THEREOF | COLOURTEX INDUSTRIES LIMITED (IN) | 2013-01-17 | — | — | WO | disclosed |