SCHEMBL14647121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647161	0.92	MGLL (0.52)	PARP1MGLLSMN1; SMN2ALDH1A1LMNA
	SCHEMBL14647270	0.89	MGLL (0.46)	PARP1MGLLNAMPTALDH1A1
	SCHEMBL14647218	0.88	MGLL (0.46)	PARP1MGLLSMN1; SMN2ALDH1A1LMNA
	SCHEMBL14647202	0.88	MAPT (0.56)	PARP1MGLLCYP2C19SMN1; SMN2CYP3A4
	SCHEMBL14647149	0.88	MAPT (0.55)	MGLLSMN1; SMN2AKR1C3ALDH1A1LMNA
	SCHEMBL14647176	0.87	MGLL (0.50)	MGLLCYP3A4NAMPTTSHR
	SCHEMBL14647260	0.85	SMN1; SMN2 (0.56)	SMN1; SMN2CYP3A4ALDH1A1LMNA
	SCHEMBL14647267	0.85	KDM4E (0.53)	PARP1SMN1; SMN2ALDH1A1HPGD
	SCHEMBL14647178	0.84	MAPT (0.52)	PARP1MGLLSMN1; SMN2ALDH1A1LMNA
	SCHEMBL14647132	0.84	MGLL (0.49)	PARP1MGLLSMN1; SMN2ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.