SCHEMBL14647176

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647202	0.89	MAPT (0.56)	MGLLKDM4EMAPTCYP3A4TSHR
	SCHEMBL14647161	0.89	MGLL (0.52)	MGLLKDM4EMAPTTSHR
	SCHEMBL14647149	0.87	MAPT (0.55)	MGLLMAPTTSHR
	SCHEMBL14647218	0.87	MGLL (0.46)	MGLLMAPTTSHR
	SCHEMBL14647121	0.87	PARP1 (0.48)	MGLLNAMPTCYP3A4TSHR
	SCHEMBL14647178	0.86	MAPT (0.52)	MGLLKDM4EMAPTTSHR
	SCHEMBL14647260	0.85	SMN1; SMN2 (0.56)	KDM4EMAPTCYP3A4
	SCHEMBL14647261	0.83	MGLL (0.49)	MGLLNAMPTKDM4EMAPTCYP3A4
	SCHEMBL15703280	0.82	MGLL (0.48)	MGLLKDM4EMAPT
	SCHEMBL14647132	0.82	MGLL (0.49)	MGLLMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.