SCHEMBL14647178

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647202	0.96	MAPT (0.56)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647161	0.88	MGLL (0.52)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647180	0.87	SMN1; SMN2 (0.51)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647261	0.87	MGLL (0.49)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647218	0.86	MGLL (0.46)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647149	0.86	MAPT (0.55)	MAPTMGLLLMNASMN1; SMN2TSHR
	SCHEMBL14647176	0.86	MGLL (0.50)	MAPTMGLLTSHRKDM4E
	SCHEMBL14647128	0.85	PARP1 (0.51)	MGLLLMNATSHRMEN1KMT2A
	SCHEMBL14647121	0.84	PARP1 (0.48)	MGLLLMNASMN1; SMN2TSHRHPGD
	SCHEMBL14647260	0.84	SMN1; SMN2 (0.56)	MAPTLMNASMN1; SMN2KDM4EHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.