SCHEMBL14647141

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647258	0.92	NPC1 (0.46)	PARP1MGLLTPSAB1HSD11B1PARP14
	SCHEMBL14647174	0.89	ALDH1A1 (0.48)	PARP1MGLLPARP14PARP10
	SCHEMBL14647128	0.85	PARP1 (0.51)	PARP1MGLL
	SCHEMBL14647222	0.84	PARP1 (0.50)	PARP1AURKB
	SCHEMBL14647129	0.84	L3MBTL3 (0.53)	PARP1
	SCHEMBL14647181	0.83	PARP1 (0.56)	PARP1
	SCHEMBL14647161	0.83	MGLL (0.52)	PARP1MGLL
	SCHEMBL14647215	0.82	L3MBTL3 (0.51)	PARP1
	SCHEMBL14647212	0.82	PARP1 (0.61)	PARP1
	SCHEMBL14647172	0.82	PARP1 (0.54)	PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.