SCHEMBL14647183

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647217	0.91	DRD4 (0.48)	PARP1DRD4DRD2DRD3GAA
	SCHEMBL14647226	0.91	TNKS (0.43)	PARP1TSHR
	SCHEMBL15703286	0.91	PARP1 (0.46)	PARP1L3MBTL1MAPTTSHR
	SCHEMBL14647192	0.91	PARP1 (0.46)	PARP1DRD4DRD2DRD3TNK2
	SCHEMBL14647187	0.90	DRD4 (0.43)	PARP1DRD4DRD2DRD3TSHR
	SCHEMBL14647158	0.90	MAPT (0.48)	PARP1DRD4MAPTGAATSHR
	SCHEMBL14647276	0.90	DRD4 (0.54)	PARP1DRD4DRD2DRD3MAPT
	SCHEMBL14647224	0.90	DRD4 (0.52)	L3MBTL1DRD4DRD2DRD3MAPT
	SCHEMBL14647230	0.89	KCNH2 (0.48)	PARP1DRD4DRD3TSHR
	SCHEMBL14647115	0.88	PARP1 (0.43)	PARP1DRD4GAATSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.