SCHEMBL14647276

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647217	0.91	DRD4 (0.48)	DRD4DRD2DRD3GAAHSD17B10
	SCHEMBL14647183	0.90	PARP1 (0.46)	DRD4DRD2DRD3GAAMAPT
	SCHEMBL14647224	0.90	DRD4 (0.52)	DRD4DRD2DRD3GAAKDM4E
	SCHEMBL14647158	0.90	MAPT (0.48)	DRD4GAAHSD17B10KDM4EMAPT
	SCHEMBL14647115	0.88	PARP1 (0.43)	DRD4GAAHSD17B10POLBTSHR
	SCHEMBL14647188	0.87	HSD17B10 (0.56)	DRD4DRD2DRD3GAAHSD17B10
	SCHEMBL14647230	0.87	KCNH2 (0.48)	DRD4DRD3TSHRHTR7PARP1
	SCHEMBL15703264	0.84	HSD17B10 (0.45)	DRD4DRD3GAAHSD17B10MAPT
	SCHEMBL14647223	0.84	SIGMAR1 (0.45)	GAAHSD17B10KDM4EALDH1A1TSHR
	SCHEMBL14647187	0.84	DRD4 (0.43)	DRD4DRD2DRD3HSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.