SCHEMBL14647115

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647217	0.91	DRD4 (0.48)	PARP1DRD4GAATSHRHSD17B10
	SCHEMBL14647243	0.89	HTR7 (0.47)	PARP1DRD4POLBKHKHTR7
	SCHEMBL14647224	0.88	DRD4 (0.52)	DRD4GAAHTR7
	SCHEMBL14647183	0.88	PARP1 (0.46)	PARP1DRD4GAATSHRPOLB
	SCHEMBL14647276	0.88	DRD4 (0.54)	PARP1DRD4GAATSHRHSD17B10
	SCHEMBL14647158	0.88	MAPT (0.48)	PARP1DRD4GAATSHRHSD17B10
	SCHEMBL14647230	0.87	KCNH2 (0.48)	PARP1DRD4TSHRKCNH2PARP2
	SCHEMBL14647188	0.85	HSD17B10 (0.56)	PARP1DRD4GAATSHRHSD17B10
	SCHEMBL14647242	0.84	PARP1 (0.51)	PARP1DRD4TSHRPARP2HTR7
	SCHEMBL14647223	0.84	SIGMAR1 (0.45)	PARP1GAATSHRHSD17B10HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.