SCHEMBL14647158

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647217	0.91	DRD4 (0.48)	DRD4PARP1TSHRGAAHSD17B10
	SCHEMBL14647276	0.90	DRD4 (0.54)	MAPTKDM4EALDH1A1DRD4PARP1
	SCHEMBL14647183	0.90	PARP1 (0.46)	MAPTDRD4PARP1TSHRGAA
	SCHEMBL14647224	0.90	DRD4 (0.52)	MAPTKDM4EALDH1A1DRD4ADRA1D
	SCHEMBL14647115	0.88	PARP1 (0.43)	KCNH2DRD4PARP1TSHRGAA
	SCHEMBL14647188	0.87	HSD17B10 (0.56)	MAPTALDH1A1DRD4PARP1TSHR
	SCHEMBL14647230	0.87	KCNH2 (0.48)	KCNH2DRD4PARP1ADRA1DADRA1A
	SCHEMBL15703264	0.84	HSD17B10 (0.45)	MAPTALDH1A1DRD4PARP1TSHR
	SCHEMBL14647223	0.84	SIGMAR1 (0.45)	KDM4EALDH1A1PARP1TSHRGAA
	SCHEMBL14647187	0.84	DRD4 (0.43)	ALDH1A1DRD4PARP1TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.