SCHEMBL14647197

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL14647156	0.92	ALDH1A1 (0.45)	ALDH1A1PARP1OPRM1OPRK1OPRL1
	SCHEMBL14647171	0.90	PARP1 (0.48)	PARP1CHRM1OPRM1OPRK1OPRL1
	SCHEMBL14647194	0.88	PARP1 (0.47)	ALDH1A1PARP1
	SCHEMBL15979575	0.86	TRPV6 (0.41)	ALDH1A1PARP1CHRM1OPRK1OPRL1
	SCHEMBL14647269	0.83	MEN1 (0.46)	ALDH1A1PARP1
	SCHEMBL14647157	0.83	PARP1 (0.54)	PARP1OPRM1OPRK1OPRL1
	SCHEMBL14647223	0.82	SIGMAR1 (0.45)	ALDH1A1TSHRPARP1OPRM1OPRK1
	SCHEMBL14647160	0.82	PARP1 (0.52)	PARP1OPRM1OPRK1OPRL1
	SCHEMBL14647225	0.80	PARP1 (0.48)	PARP1
	SCHEMBL14647189	0.80	PARP1 (0.43)	PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.