Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ABCC1 | P33527 | 8/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5800196 | 0.81 | CASR (0.69) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 | |
| SCHEMBL1462922 | 0.77 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 | |
| SCHEMBL5928860 | 0.73 | SMN1; SMN2 (0.70) | SMN1; SMN2TSHRMEN1KMT2ACYP1A2 | |
| SCHEMBL1464668 | 0.73 | PTPN1 (0.49) | ALDH1A1 | |
| SCHEMBL5780401 | 0.72 | CASR (0.69) | ALDH1A1SMN1; SMN2TSHRABCC1CYP1A2 | |
| SCHEMBL28207160 | 0.72 | KMT2A (0.55) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 | |
| SCHEMBL1463678 | 0.71 | MEN1 (0.59) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 | |
| SCHEMBL1463935 | 0.71 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 | |
| SCHEMBL874609 | 0.71 | ADRA1B (0.69) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP1A2 | |
| SCHEMBL1326596 | 0.70 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | GUANGZHOU INSTITUTE OF BIOMEDICINE AND HEALTH, CHINESE ACADEMY OF SCIENCES (CN) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071148-A1 | COMPOUNDS AS THE ESTROGEN RELATED RECEPTORS MODULATORS AND THE USES THEREOF | ESRRA, ESRRB, ESRRG | ALDH1A1 412/4885SMN1; SMN2 4538/4885TSHR 321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.