Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9389800 | 0.85 | ALDH1A1 (0.54) | HPGDALDH1A1TNK2MEN1KMT2A | |
| SCHEMBL1129558 | 0.83 | ALDH1A1 (0.44) | HPGDALDH1A1HTTCES2CES1 | |
| SCHEMBL169922 | 0.83 | MCL1 (0.49) | HPGDALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL27351823 | 0.77 | HPGD (0.51) | HPGDALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL9680888 | 0.77 | AKR1C3 (0.44) | HPGDALDH1A1TNK2MEN1KMT2A | |
| SCHEMBL11355326 | 0.76 | HTT (0.45) | HPGDALDH1A1HTTMAPK1KMT2A | |
| SCHEMBL21132553 | 0.76 | HPGD (0.56) | HPGDALDH1A1HTTMAPK1MEN1 | |
| SCHEMBL29723381 | 0.76 | HPGD (0.56) | HPGDALDH1A1HTTMAPK1MEN1 | |
| SCHEMBL28926437 | 0.75 | HPGD (0.43) | HPGDALDH1A1HTTCES2CES1 | |
| SCHEMBL4770419 | 0.74 | SRD5A2 (0.59) | HPGDCES2CES1HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9201319-B2 | Image bearing member, manufacturing method of the same, image forming method, image forming apparatus, and process cartridge | RICOH COMPANY, LTD. (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140178810-A1 | IMAGE BEARING MEMBER, MANUFACTURING METHOD OF THE SAME, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2014-06-26 | — | — | US | disclosed |
| US-8679712-B2 | Photoreceptor and image forming method, image forming apparatus, and process cartridge using the photoreceptor | RICOH COMPANY, LTD. (JP) | 2014-03-25 | — | — | US | disclosed |
| US-20130295497-A1 | ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE | RICOH COMPANY, LTD. (JP) | 2013-11-07 | — | — | US | disclosed |
| US-20130022903-A1 | PHOTORECEPTOR AND IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE USING THE PHOTORECEPTOR | RICOH COMPANY, LTD. (JP) | 2013-01-24 | — | — | US | disclosed |