Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28926398 | 0.83 | POLB (0.53) | HPGDALDH1A1HTTMEN1KMT2A | |
| SCHEMBL29822849 | 0.80 | CES2 (0.38) | HPGDALDH1A1RAB9ANPC1POLB | |
| SCHEMBL16344312 | 0.77 | HPGD (0.47) | HPGDALDH1A1MEN1KMT2ACYP2C9 | |
| SCHEMBL14650448 | 0.75 | HPGD (0.45) | HPGDALDH1A1HTTMAPK1MEN1 | |
| SCHEMBL28926370 | 0.73 | GAA (0.42) | HPGDALDH1A1RAB9ANPC1POLB | |
| SCHEMBL28965092 | 0.73 | CCR5 (0.43) | HPGDRAB9APOLBCES2CES1 | |
| SCHEMBL9966338 | 0.72 | POLB (0.45) | HPGDRAB9APOLBCES2CES1 | |
| SCHEMBL16150815 | 0.70 | FASN (0.73) | HPGDALDH1A1HTTPOLB | |
| SCHEMBL25020656 | 0.69 | ALDH1A1 (0.38) | HPGDALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL9474091 | 0.69 | HPGD (0.35) | HPGDALDH1A1HTTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115385876-A | Method for constructing C-C bond by photocatalytic activation of alpha-position C-H bond of tetrahydrofuran | 中国科学院理化技术研究所 | 2022-11-25 | — | — | CN | disclosed |