Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.65 |
| ▸ | STAT3 | P40763 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HTR1A | P08908 | 3/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | RGS12 | O14924 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28691795 | 0.86 | HTR1A (0.51) | TERTHTR1ADRD2HTR6MEN1 | |
| SCHEMBL14650636 | 0.85 | TERT (0.49) | TERTSTAT3HIF1AHTR1ADRD2 | |
| SCHEMBL8556091 | 0.82 | HTR1A (0.73) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL6275178 | 0.82 | KDM4E (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL28704128 | 0.81 | CYP1B1 (0.60) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL3117603 | 0.79 | TERT (1.00) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL1463660 | 0.79 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL6306405 | 0.78 | HTR1A (0.54) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8559706 | 0.78 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A | |
| SCHEMBL8559095 | 0.78 | HTR1A (0.69) | HTR1ADRD2HTR6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4544544-A1 | DETECTING LONGITUDINAL PROGRESSION OF ALZHEIMER'S DISEASE (AD) BASED ON SPEECH ANALYSES | Genentech Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| US-20250107746-A1 | DETECTING LONGITUDINAL PROGRESSION OF ALZHEIMER'S DISEASE (AD) BASED ON SPEECH ANALYSES | GENENTECH INC (US) | 2025-04-03 | — | — | US | disclosed |
| CN-119404251-A | Detection of longitudinal progression of Alzheimer's Disease (AD) based on speech analysis | 基因泰克公司 | 2025-02-07 | — | — | CN | disclosed |
| EP-4494141-A1 | PREDICTING NEURODEGENERATIVE DISEASES BASED ON SPEECH ANALYSES | GENENTECH, INC. (US) | 2025-01-22 | — | — | EP | disclosed |
| US-20250000446-A1 | PREDICTING NEURODEGENERATIVE DISEASES BASED ON SPEECH ANALYSES | GENENTECH INC (US) | 2025-01-02 | — | — | US | disclosed |
| CN-118871989-A | Predicting neurodegenerative diseases based on speech analysis | 基因泰克公司 | 2024-10-29 | — | — | CN | disclosed |
| WO-2023250326-A1 | DETECTING LONGITUDINAL PROGRESSION OF ALZHEIMER'S DISEASE (AD) BASED ON SPEECH ANALYSES | GENENTECH, INC. (US) | 2023-12-28 | — | — | WO | disclosed |
| WO-2023178049-A1 | PREDICTING NEURODEGENERATIVE DISEASES BASED ON SPEECH ANALYSES | GENENTECH, INC. (US) | 2023-09-21 | — | — | WO | disclosed |