Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14650636 | 0.91 | TERT (0.49) | TERTHTR1ADRD2HTR6MAOB | |
| SCHEMBL14650669 | 0.86 | STAT3 (0.44) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650664 | 0.83 | STAT3 (0.42) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650685 | 0.81 | CYP1B1 (0.46) | TERTMAOBSTAT3HIF1AMEN1 | |
| SCHEMBL14650540 | 0.79 | TERT (0.40) | TERTHTR1ADRD2HTR6MAOB | |
| SCHEMBL30574144 | 0.79 | TERT (0.65) | TERTHTR1ADRD2HTR6STAT3 | |
| SCHEMBL14650695 | 0.78 | TERT (0.33) | TERTSTAT3HIF1A | |
| SCHEMBL14650683 | 0.77 | STAT3 (0.37) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650700 | 0.77 | TERT (0.37) | TERTSTAT3HIF1AMEN1KMT2A | |
| SCHEMBL14650588 | 0.76 | STAT3 (0.51) | TERTSTAT3HIF1AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051468-B2 | Dyes for polymer coloration, their preparation and their use | CLARIANT INTERNATIONAL LTD (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20130019415-A1 | DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2013-01-24 | — | — | US | disclosed |