Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.40 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14348069 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL14348073 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL14651109 | 1.00 | ALDH1A1 (0.43) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL14651076 | 0.85 | GAA (0.39) | NPC1GAAPOLB | |
| SCHEMBL14514251 | 0.85 | GAA (0.39) | NPC1GAAPOLB | |
| SCHEMBL13039150 | 0.80 | ALDH1A1 (0.47) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL16765456 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL28833793 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL26621555 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 | |
| SCHEMBL28833794 | 0.79 | ALDH1A1 (0.51) | ALDH1A1HPGDSMN1; SMN2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772450-B2 | Beta-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-07-08 | — | — | US | disclosed |
| US-20130023644-A1 | BETA-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2013-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130023644-A1 | BETA-AMINO ACIDS | BCAT1, MARCKS, YWHAZ | ALDH1A1 4837/4885HPGD 3313/4885SMN1; SMN2 4026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.