SCHEMBL146546

SCHEMBL146546

CC(N)c1cccc(F)c1

nearest known ligand 0.63

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.48
TDO2 P48775 1/20 0.48
AOC3 Q16853 1/20 0.46
ACHE P22303 1/20 0.44
HDAC4 P56524 1/20 0.44
HDAC7 Q8WUI4 1/20 0.44
HDAC5 Q9UQL6 1/20 0.44
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
OPRM1 P35372 1/20 0.41
OPRD1 P41143 1/20 0.41
OPRK1 P41145 1/20 0.41
OPRL1 P41146 1/20 0.41
SLC6A2 P23975 1/20 0.41
SLC6A4 P31645 1/20 0.41
CASR P41180 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL800515 1.00 IDO1 (0.48) IDO1TDO2AOC3ACHEHDAC4
SCHEMBL781357 1.00 IDO1 (0.48) IDO1TDO2AOC3ACHEHDAC4
SCHEMBL29876183 1.00 IDO1 (0.48) IDO1TDO2AOC3ACHEHDAC4
Hydrochloric Acid SCHEMBL780403 0.98 IDO1 (0.52) IDO1TDO2AOC3ACHEHDAC4
Bromide SCHEMBL28591637 0.98 IDO1 (0.47) IDO1TDO2AOC3ACHEHDAC4
Hydrochloric Acid SCHEMBL1239204 0.98 IDO1 (0.52) IDO1TDO2AOC3ACHEHDAC4
Iodide SCHEMBL29040444 0.98 IDO1 (0.47) IDO1TDO2AOC3ACHEHDAC4
Hydrochloric Acid SCHEMBL507110 0.98 IDO1 (0.52) IDO1TDO2AOC3ACHEHDAC4
SCHEMBL31020152 0.85 IDO1 (0.44) IDO1TDO2AOC3ACHEHDAC4
SCHEMBL659099 0.83 ADRB2 (0.46) SLC6A2SLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120049017-A Org/ZnSO4Electrolyte, preparation method thereof and application of electrolyte in secondary battery 同济大学 2025-05-27 CN claimed
CN-114420852-B Preparation method of pure-phase RP perovskite film 河北工业大学 2025-05-27 CN claimed
CN-120004697-A Preparation method of OrgVO material and application of OrgVO material as secondary battery anode material 同济大学 2025-05-16 CN claimed
CN-119726348-A Near-infrared perovskite laser and preparation method thereof 中国科学院半导体研究所 2025-03-28 CN claimed
CN-119726347-A Non-external-cavity near-infrared perovskite laser and preparation method thereof 中国科学院半导体研究所 2025-03-28 CN claimed
CN-119431706-A Fatigue-resistant polyurethane elastomer and preparation method and application thereof 万勋科技(深圳)有限公司 2025-02-14 CN claimed
CN-119371337-A Metal halide perovskite nanocrystalline resistant to heat-induced fluorescence quenching, and preparation method and application thereof 华南理工大学 2025-01-28 CN claimed
CN-118507836-B Electrolyte for secondary lithium metal battery 深圳欣界能源科技有限公司 2024-09-17 CN claimed
CN-118531558-A Mixed-dimension perovskite nanofiber membrane with high fluorescence stability and preparation method thereof 武汉纺织大学 2024-08-23 CN claimed
CN-118531514-A Mixed-dimension perovskite/polymer composite filament, preparation method and application 武汉纺织大学 2024-08-23 CN claimed
US-20090148921-A1 Compositions and methods for enhancing apoptosis GENENTECH, INC. (US) 2009-06-11 US claimed
CN-101410366-A Substituted bicyclic ring derivatives and uses thereof ASAHI KASEI PHARMA CORP (JP) 2009-04-15 CN claimed
US-20090054401-A1 Substituted bicyclic derivatives and use thereof ASAHI KASEI PHARMA CORPORATION (JP) 2009-02-26 US claimed
EP-2006271-A2 SUBSTITUTED BICYCLIC CYCLIC DERIVATIVE AND USE THEREOF Asahi Kasei Pharma Corporation (JP) 2008-12-24 EP claimed
EP-1590666-B1 COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS GENENTECH INC (US) 2008-07-09 EP claimed
EP-1590666-A4 COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS GENENTECH INC (US) 2006-07-26 EP claimed
EP-1590666-A1 COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS Genentech, Inc. (US) 2005-11-02 EP claimed
US-20040171554-A1 Compositions and methods for enhancing apoptosis GENENTECH, INC. 2004-09-02 US claimed
WO-2004072641-A1 COMPOSITIONS AND METHODS FOR ENHANCING APOPTOSIS GENENTECH, INC. (US) 2004-08-26 WO claimed
US-4209638-A RESOLUTION OF ENANTIOMORPHS THE BOOTS COMPANY LIMITED (GB) 1980-06-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054401-A1 Substituted bicyclic derivatives and use thereof LTB4R2, LTC4S, LTB4R IDO1 481/4885TDO2 311/4885AOC3 1048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.