Trifluoromethanesulfonic Acid

Trifluoromethanesulfonic Acid

SCHEMBL14655600

CC(C)c1ccnc(-c2ccccc2)c1.O=S(=O)(O)C(F)(F)F.[Ir]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPKAPK2 P49137 3/20 0.41
ASIC3 Q9UHC3 1/20 0.39
PTPN5 P54829 3/20 0.39
KAT6A Q92794 2/20 0.38
PTPN1 P18031 1/20 0.37
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
LMNA P02545 2/20 0.36
RAB9A P51151 2/20 0.36
S1PR4 O95977 1/20 0.36
TP53 P04637 1/20 0.36
POLB P06746 1/20 0.36
HPGD P15428 1/20 0.36
S1PR1 P21453 1/20 0.36
SDHB P21912 1/20 0.36
MAPK1 P28482 1/20 0.36
STAT3 P40763 1/20 0.36
STAT1 P42224 1/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoromethanesulfonic Acid SCHEMBL14655602 0.87 MAPKAPK2 (0.41) MAPKAPK2ASIC3PTPN5KAT6APTPN1
Trifluoromethanesulfonic Acid SCHEMBL14655601 0.87 MAPKAPK2 (0.41) MAPKAPK2ASIC3PTPN5KAT6APTPN1
SCHEMBL27907882 0.83 ASIC3 (0.47) MAPKAPK2ASIC3LMNARAB9ATGFBR1
SCHEMBL14054103 0.83 ASIC3 (0.53) MAPKAPK2ASIC3LMNARAB9ATGFBR1
Trifluoromethanesulfonic Acid SCHEMBL14655597 0.82 CYP2A6 (0.51) ASIC3KAT6APTPN1MEN1KMT2A
Hydrochloric Acid SCHEMBL28148517 0.81 ASIC3 (0.52) MAPKAPK2ASIC3KMT2ALMNARAB9A
Trifluoromethanesulfonic Acid SCHEMBL14655479 0.80 FFAR1 (0.44) PTPN5MEN1KMT2ALMNARAB9A
SCHEMBL25456048 0.80 ASIC3 (0.50) MAPKAPK2ASIC3LMNARAB9ATGFBR1
Trifluoromethanesulfonic Acid SCHEMBL14655584 0.79 LOXL2 (0.40) ASIC3KAT6APTPN1MEN1KMT2A
Trifluoromethanesulfonic Acid SCHEMBL28946874 0.78 ASIC3 (0.42) MAPKAPK2ASIC3KAT6APTPN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2024-04-25 US disclosed
US-11910700-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2024-02-20 US disclosed
US-20220302396-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2022-09-22 US disclosed
US-11380854-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2022-07-05 US disclosed
US-20190245153-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2019-08-08 US disclosed
US-10312458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2019-06-04 US disclosed
US-20160099425-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION 2016-04-07 US disclosed
US-9184397-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2015-11-10 US disclosed
EP-2551933-B1 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORP (US) 2014-09-24 EP disclosed
US-20140159028-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2014-06-12 US disclosed
US-8709615-B2 Heteroleptic iridium complexes as dopants UNIVERSAL DISPLAY CORPORATION (US) 2014-04-29 US disclosed
US-20130026452-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS UNIVERSAL DISPLAY CORPORATION (US) 2013-01-31 US disclosed
EP-2551933-A1 Heteroleptic iridium complexes as dopants Universal Display Corporation (US) 2013-01-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160099425-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-20140159028-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-20190245153-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-10312458-B2 Organic electroluminescent materials and devices JUND, OCIAD1, OCIAD2 MAPKAPK2 2295/4885ASIC3 1921/4885PTPN5 4523/4885
US-20240138251-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-20130026452-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-11380854-B2 Heteroleptic iridium complexes as dopants JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-11910700-B2 Heteroleptic iridium complexes as dopants JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885
US-20220302396-A1 HETEROLEPTIC IRIDIUM COMPLEXES AS DOPANTS JUND, DRD2, DRD1 MAPKAPK2 3122/4885ASIC3 3658/4885PTPN5 3996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.