Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.52 |
| ▸ | MAPK12 | P53778 | 11/20 | 0.52 |
| ▸ | HCK | P08631 | 8/20 | 0.49 |
| ▸ | SRC | P12931 | 8/20 | 0.49 |
| ▸ | GSK3A | P49840 | 7/20 | 0.49 |
| ▸ | SYK | P43405 | 5/20 | 0.49 |
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656383 | 1.00 | MAPK14 (0.52) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656426 | 0.93 | MAPK12 (0.54) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656155 | 0.93 | MAPK12 (0.54) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656152 | 0.93 | MAPK12 (0.54) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656457 | 0.93 | MAPK14 (0.57) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656512 | 0.93 | MAPK14 (0.57) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656455 | 0.93 | MAPK14 (0.57) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14668280 | 0.92 | MAPK14 (0.54) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL19732099 | 0.92 | MAPK12 (0.42) | MAPK14MAPK12HCKSRCGSK3A | |
| SCHEMBL14656219 | 0.91 | MAPK14 (0.49) | MAPK14MAPK12HCKSRCGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | RESPIVERT LIMITED (GB) | 2018-06-19 | — | — | US | claimed |
| US-20170362208-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2017-12-21 | — | — | US | claimed |
| US-9771354-B2 | Pyrazole p38 map kinase inhibitors | RESPIVERT LTD. (GB) | 2017-09-26 | — | — | US | claimed |
| US-20160130256-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2016-05-12 | — | — | US | claimed |
| EP-2556065-B1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD (GB) | 2014-12-17 | — | — | EP | claimed |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD. (GB) | 2013-01-31 | — | — | US | claimed |
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | RESPIVERT LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-20170362208-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2017-12-21 | — | — | US | disclosed |
| US-9771354-B2 | Pyrazole p38 map kinase inhibitors | RESPIVERT LTD. (GB) | 2017-09-26 | — | — | US | disclosed |
| US-20160130256-A1 | NOVEL COMPOUNDS | RESPIVERT LIMITED (GB) | 2016-05-12 | — | — | US | disclosed |
| EP-2556065-B1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD (GB) | 2014-12-17 | — | — | EP | disclosed |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | RESPIVERT LTD. (GB) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170362208-A1 | NOVEL COMPOUNDS | ARG1, IL1B, LTB4R | MAPK14 4207/4885MAPK12 3555/4885HCK 4707/4885 |
| US-10000471-B2 | Pyrazole P38 map kinase inhibitors | MAPK1, MAP3K1, MAPK3 | MAPK14 31/4885MAPK12 41/4885HCK 1243/4885 |
| US-20160130256-A1 | NOVEL COMPOUNDS | ARG1, IL1B, LTB4R | MAPK14 4207/4885MAPK12 3555/4885HCK 4707/4885 |
| US-20130029990-A1 | PYRAZOLE P38 MAP KINASE INHIBITORS | MAPK1, MAP3K1, MAPK3 | MAPK14 31/4885MAPK12 41/4885HCK 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.