Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | EDNRA | P25101 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | FABP3 | P05413 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 1/20 | 0.38 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14656964 | 0.86 | NR4A2 (0.51) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL14657482 | 0.85 | ALDH1A1 (0.73) | ALDH1A1KDM4EATML3MBTL1GAA | |
| SCHEMBL2790066 | 0.84 | KDM4E (0.51) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL25557692 | 0.84 | L3MBTL1 (0.62) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL11981026 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL14900748 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL29354385 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL29387946 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL11981068 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 | |
| SCHEMBL5999723 | 0.83 | L3MBTL1 (0.72) | ALDH1A1KDM4EATML3MBTL1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422287-B2 | Bridged triarylamines and -phosphines as materials for electronic devices | MERCK PATENT GMBH (DE) | 2016-08-23 | — | — | US | disclosed |
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130026422-A1 | BRIDGED TRIARYLAMINES AND -PHOSPHINES AS MATERIALS FOR ELECTRONIC DEVICES | TEC, PNMT, TES | ALDH1A1 612/4885KDM4E 2344/4885ATM 1707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.