Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5443290 | 0.85 | TRPV1 (0.61) | TRPV1 | |
| SCHEMBL14657227 | 0.81 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL5451436 | 0.80 | TRPV1 (0.57) | TRPV1 | |
| SCHEMBL5443305 | 0.75 | TRPV1 (0.76) | TRPV1 | |
| SCHEMBL14657219 | 0.73 | TRPV1 (0.66) | TRPV1 | |
| SCHEMBL5445612 | 0.73 | TDO2 (0.62) | TRPV1 | |
| SCHEMBL5022397 | 0.73 | TRPV1 (0.74) | TRPV1 | |
| SCHEMBL14663532 | 0.72 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL3104055 | 0.70 | TRPV1 (1.00) | TRPV1 | |
| SCHEMBL14658104 | 0.70 | TRPV1 (0.57) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2736899-A1 | SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2014-06-04 | — | — | EP | claimed |
| US-20130029995-A1 | Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-01-31 | — | — | US | claimed |
| WO-2013013816-A1 | SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2013-01-31 | — | — | WO | claimed |
| US-9029378-B2 | Substituted bicyclic aromatic carboxamide and urea compounds as vanilloid receptor ligands | GRUENENTHAL GMBH (DE) | 2015-05-12 | — | — | US | disclosed |
| EP-2736899-A1 | SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-20130029995-A1 | Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | GRUENENTHAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
| WO-2013013816-A1 | SUBSTITUTED BICYCLIC AROMATIC CARBOXAMIDE AND UREA DERIVATIVES AS VANILLOID RECEPTOR LIGANDS | Grünenthal GmbH (DE) | 2013-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029995-A1 | Substituted Bicyclic Aromatic Carboxamide and Urea Compounds as Vanilloid Receptor Ligands | TRPV1, TRPV2, TRPV4 | TRPV1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.