Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 2/20 | 0.35 |
| ▸ | ADH1C | P00326 | 2/20 | 0.35 |
| ▸ | ADH1A | P07327 | 2/20 | 0.35 |
| ▸ | ADH7 | P40394 | 2/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14660240 | 1.00 | TSHR (0.52) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL14010386 | 0.89 | — | — | |
| SCHEMBL27618199 | 0.81 | MAPT (0.42) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL3463522 | 0.81 | TSHR (0.48) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL875561 | 0.80 | — | — | |
| SCHEMBL10432807 | 0.79 | ADH1B (0.50) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL17509727 | 0.79 | ADH1B (0.50) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL9576172 | 0.79 | ADH1B (0.50) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL28582956 | 0.79 | ADH1B (0.50) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH | |
| SCHEMBL7104793 | 0.79 | ADH1B (0.50) | TSHRSMN1; SMN2TRPA1DDAH1GAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2559720-A1 | CROSSLINKED COMPOSITION | Daicel Corporation (JP) | 2013-02-20 | — | — | EP | disclosed |
| US-20130026458-A1 | CROSSLINKABLE COMPOSITION | DAICEL CORPORATION (JP) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130026458-A1 | CROSSLINKABLE COMPOSITION | DDC, ODC1, SRM | TSHR 4686/4885SMN1; SMN2 2545/4885TRPA1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.