Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | AGXT | P21549 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219340 | 0.98 | TSHR (0.44) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| Boric Acid SCHEMBL28103363 | 0.92 | LIPE (0.43) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| Boric Acid SCHEMBL28083957 | 0.83 | IDO1 (0.44) | IDO1AGXT | |
| SCHEMBL1356758 | 0.81 | TSHR (0.48) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL29219369 | 0.78 | CA1 (0.43) | ALDH1A1IDO1CA1CA2CA9 | |
| SCHEMBL8775678 | 0.78 | TSHR (0.44) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL14232277 | 0.77 | MRGPRX4 (0.54) | ALDH1A1 | |
| SCHEMBL10940340 | 0.76 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL5016440 | 0.76 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 | |
| SCHEMBL726130 | 0.76 | TSHR (0.52) | TSHRALDH1A1IDO1AGXTSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9243004-B2 | Synthesis of boronic esters and boronic acids using grignard reagents | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-01-26 | — | — | US | disclosed |
| US-20150119580-A1 | SYNTHESIS OF BORONIC ESTERS AND BORONIC ACIDS USING GRIGNARD REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-04-30 | — | — | US | disclosed |
| WO-2013016185-A1 | SYNTHESIS OF BORONIC ESTERS AND BORONIC ACIDS USING GRIGNARD REAGENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-01-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119580-A1 | SYNTHESIS OF BORONIC ESTERS AND BORONIC ACIDS USING GRIGNARD REAGENTS | AGL, DBF4, ME1 | TSHR 4162/4885ALDH1A1 3954/4885IDO1 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.