Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.55 |
| ▸ | TLR2 | O60603 | 3/20 | 0.50 |
| ▸ | TLR1 | Q15399 | 3/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628667 | 0.89 | TRPM8 (0.50) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL3392306 | 0.89 | TRPM8 (0.49) | TAAR1TRPM8POLBALDH1A1KDM4E | |
| SCHEMBL2628617 | 0.89 | TRPM8 (0.49) | TAAR1TRPM8POLBALDH1A1KDM4E | |
| SCHEMBL24540522 | 0.89 | TRPM8 (0.50) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL2628712 | 0.89 | TRPM8 (0.50) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL24540473 | 0.89 | TRPM8 (0.49) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL2628702 | 0.88 | ALDH1A1 (0.55) | TRPM8ALDH1A1EPHX1MEN1KMT2A | |
| SCHEMBL2628656 | 0.88 | TRPM8 (0.48) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL2628669 | 0.88 | TRPM8 (0.48) | TAAR1TRPM8POLBALDH1A1EPHX1 | |
| SCHEMBL24540254 | 0.88 | TAAR1 (0.54) | TAAR1TRPM8POLBEPHX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362264-B2 | Tryptophan antagonist; anticancer agents | DENDREON CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |
| US-8362264-B2 | Tryptophan antagonist; anticancer agents | DENDREON CORPORATION (US) | 2013-01-29 | — | — | US | disclosed |