Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESRRB | O95718 | 1/20 | 0.39 |
| ▸ | ESRRG | P62508 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628617 | 1.00 | TRPM8 (0.49) | TRPM8KDM4EF13A1TRPV1EPHX1 | |
| SCHEMBL2628712 | 0.91 | TRPM8 (0.50) | TRPM8TRPV1EPHX1TAAR1HSD17B10 | |
| SCHEMBL24540522 | 0.91 | TRPM8 (0.50) | TRPM8EPHX1TAAR1ALDH1A1POLB | |
| SCHEMBL24540473 | 0.91 | TRPM8 (0.49) | TRPM8TRPV1EPHX1TAAR1HSD17B10 | |
| SCHEMBL2628667 | 0.91 | TRPM8 (0.50) | TRPM8EPHX1TAAR1ALDH1A1POLB | |
| SCHEMBL2628702 | 0.89 | ALDH1A1 (0.55) | TRPM8TRPV1EPHX1HSD17B10ALDH1A1 | |
| SCHEMBL2628656 | 0.89 | TRPM8 (0.48) | TRPM8TRPV1EPHX1TAAR1HSD17B10 | |
| SCHEMBL14664178 | 0.89 | TAAR1 (0.55) | TRPM8KDM4EEPHX1TAAR1ALDH1A1 | |
| SCHEMBL2628669 | 0.89 | TRPM8 (0.48) | TRPM8EPHX1TAAR1HSD17B10ALDH1A1 | |
| SCHEMBL1629039 | 0.89 | TAAR1 (0.54) | TRPM8EPHX1TAAR1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056636-A1 | N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof | GIVAUDAN NEDERLAND SERVICES B.V. (NL) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056636-A1 | N-Substituted-P-Menthane-3-Carboxamide and Uses Thereof | ME2, NAPEPLD, TRPM7 | TRPM8 13/4885KDM4E 417/4885F13A1 3043/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.