Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5935349 | 0.84 | MEN1 (0.35) | CYP1A2ALOX15NFKB1MAOAMAOB | |
| SCHEMBL5935091 | 0.84 | — | — | |
| SCHEMBL5746721 | 0.81 | MEN1 (0.39) | CYP1A2ALOX15NFKB1MAOAMAOB | |
| SCHEMBL3585836 | 0.78 | CYP1A2 (0.46) | CYP1A2ALOX15NFKB1MAOAMAOB | |
| SCHEMBL13181238 | 0.77 | MIF (0.31) | CYP1A2 | |
| SCHEMBL251998 | 0.77 | LMNA (0.43) | CYP1A2ALOX15BLM | |
| Methyl Alcohol SCHEMBL17025261 | 0.75 | LMNA (0.41) | CYP1A2 | |
| SCHEMBL4430508 | 0.75 | MIF (0.39) | — | |
| SCHEMBL5819428 | 0.75 | MEN1 (0.50) | CYP1A2 | |
| SCHEMBL8276648 | 0.75 | SMN1; SMN2 (0.42) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8361779-B2 | Buffer compounds | SACHEM, INC. (US) | 2013-01-29 | — | — | US | disclosed |