Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | DHPS | P49366 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7478514 | 0.83 | CYP1A2 (0.32) | CYP1A2ALOX15NFKB1MAOAMAOB | |
| SCHEMBL31085541 | 0.79 | ALDH1A1 (0.42) | CYP1A2NOS2 | |
| SCHEMBL14665014 | 0.78 | CYP1A2 (0.42) | CYP1A2ALOX15NFKB1MAOAMAOB | |
| SCHEMBL3582821 | 0.75 | — | — | |
| SCHEMBL26921963 | 0.71 | NOS2 (0.42) | CYP1A2NFKB1BLMNOS2DDAH1 | |
| SCHEMBL689587 | 0.71 | — | — | |
| SCHEMBL6155643 | 0.70 | NOS2 (0.37) | NOS2 | |
| SCHEMBL13484050 | 0.69 | NOS2 (0.79) | CYP1A2NFKB1BLMNOS2DDAH1 | |
| SCHEMBL995818 | 0.69 | NOS2 (0.79) | CYP1A2NFKB1BLMNOS2DDAH1 | |
| SCHEMBL196828 | 0.69 | NOS2 (0.79) | CYP1A2NFKB1BLMNOS2DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2495245-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2012-09-05 | — | — | EP | disclosed |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | CHOI WOO-BAEG | 2010-03-25 | — | — | US | disclosed |
| US-7632828-B2 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. (US) | 2009-12-15 | — | — | US | disclosed |
| EP-1765821-A4 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS INC (US) | 2009-05-20 | — | — | EP | disclosed |
| EP-1765821-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB Synthesis, Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | FOB SYNTHESIS, INC. | 2006-04-06 | — | — | US | disclosed |
| WO-2005123069-A2 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | FOB SYNTHESIS, INC. (US) | 2005-12-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060074070-A1 | Gram-positive carbapenem antibacterials and processes for their preparation | MGAM, GSK3B, GSK3A | CYP1A2 3646/4885ALOX15 4111/4885NFKB1 1729/4885 |
| US-20100075945-A1 | GRAM-POSITIVE CARBAPENEM ANTIBACTERIALS AND PROCESSES FOR THEIR PREPARATION | MGAM, GSK3B, GSK3A | CYP1A2 3646/4885ALOX15 4111/4885NFKB1 1729/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.