Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | PLEC | Q15149 | 1/20 | 0.39 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942845 | 0.89 | HDAC1 (0.42) | PTGER4LNPEPERAP2HDAC1HDAC3 | |
| SCHEMBL14667441 | 0.86 | HSD17B10 (0.47) | HDAC1HDAC3ALDH1A1KDM4EMAPT | |
| SCHEMBL15942868 | 0.85 | KMT2A (0.46) | HDAC1HDAC3MEN1KMT2AALDH1A1 | |
| SCHEMBL15942847 | 0.85 | LNPEP (0.45) | LNPEPERAP2 | |
| SCHEMBL15942856 | 0.83 | ERAP2 (0.48) | LNPEPERAP2 | |
| SCHEMBL14668915 | 0.82 | ERAP2 (0.47) | LNPEPERAP2ALDH1A1LMNA | |
| SCHEMBL14667412 | 0.82 | LNPEP (0.47) | LNPEPERAP2 | |
| SCHEMBL14667535 | 0.82 | LNPEP (0.37) | PTGER4LNPEPERAP2HDAC1HDAC3 | |
| SCHEMBL14667392 | 0.82 | HDAC3 (0.51) | HDAC1HDAC3ALDH1A1MAPTHPGD | |
| SCHEMBL27378870 | 0.81 | KDM4E (0.48) | PTGER4LNPEPERAP2HDAC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | PTGER4 3883/4885LNPEP 1080/4885ERAP2 4669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.