Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 15/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 15/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 11/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 9/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15942858 | 0.88 | ALDH1A1 (0.49) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL14671096 | 0.87 | HDAC3 (0.51) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL14667441 | 0.84 | HSD17B10 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL14667384 | 0.82 | PTGER4 (0.48) | HDAC3HDAC1HDAC2MAPTHPGD | |
| SCHEMBL14667495 | 0.80 | HDAC3 (0.47) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL14667400 | 0.79 | HPGD (0.52) | MAPTHSD17B10HPGDALOX12ALDH1A1 | |
| SCHEMBL15942870 | 0.78 | MAPT (0.48) | MAPTHSD17B10HPGDALDH1A1LMNA | |
| SCHEMBL15942845 | 0.78 | HDAC1 (0.42) | HDAC3HDAC1HDAC2MAPTHPGD | |
| SCHEMBL14667390 | 0.77 | DDX3X (0.50) | HDAC3HDAC1HDAC2HDAC10HDAC6 | |
| SCHEMBL15942884 | 0.76 | XIAP (0.45) | MAPTHSD17B10ALDH1A1USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-8802448-B2 | Mixed mode ligands | PALL CORPORATION (US) | 2014-08-12 | — | — | US | disclosed |
| US-20130030154-A1 | MIXED MODE LIGANDS | PALL CORPORATION (US) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130030154-A1 | MIXED MODE LIGANDS | NCL, NECTIN4, NCLN | HDAC3 1717/4885HDAC1 1112/4885HDAC2 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.