SCHEMBL14667490

SCHEMBL14667490

C/C=N/Oc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.42
LTA4H P09960 3/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 3/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
KCNA3 P22001 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
HTT P42858 2/20 0.33
ALDH1A1 P00352 2/20 0.33
NPC1 O15118 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.32
TRPA1 O75762 1/20 0.32
CA5A P35218 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PGR P06401 1/20 0.31
HPGD P15428 1/20 0.31
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4151574 1.00 CA4 (0.42) CA4LTA4HTSHRLMNATDP1
SCHEMBL22129143 0.79 LTA4H (0.43) CA4LTA4HTSHRLMNATDP1
SCHEMBL27016003 0.76 CA4 (0.44) CA4LTA4HTSHRLMNATDP1
SCHEMBL4155588 0.75 LTA4H (0.39) CA4LTA4HTSHRLMNATDP1
SCHEMBL22485139 0.75 LTA4H (0.39) CA4LTA4HTSHRLMNATDP1
SCHEMBL6193818 0.75 LTA4H (0.39) CA4LTA4HTSHRTDP1L3MBTL1
SCHEMBL16760862 0.75 CA4 (0.42) CA4LTA4HTSHRLMNAL3MBTL1
SCHEMBL21428538 0.75 CA4 (0.37) CA4LTA4HTSHRLMNAL3MBTL1
SCHEMBL9945371 0.75 LTA4H (0.38) CA4LTA4HTSHRLMNAL3MBTL1
SCHEMBL9944297 0.75 MAPK1 (0.38) CA4LTA4HTSHRLMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140200134-A1 Anthranilamide Compounds and their use as Pesticides BASF SE (DE) 2014-07-17 US disclosed
US-8772290-B2 Alpha-arylmethoxyacrylate derivative, preparation method thereof, and pharmaceutical composition containing same Oscotech Inc. (KR) 2014-07-08 US disclosed
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES BASF SE (DE) 2014-06-19 US disclosed
US-8722678-B2 Fungicidal oximes and hydrazones E I DU PONT DE NEMOURS AND COMPANY (US) 2014-05-13 US disclosed
US-20130030002-A1 FUNGICIDAL OXIMES AND HYDRAZONES E I DUPONT DE NEMOURS AND COMPANY (US) 2013-01-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140200134-A1 Anthranilamide Compounds and their use as Pesticides ANTXR2, NQO2, AAAS CA4 298/4885LTA4H 1075/4885TSHR 3329/4885
US-20130030002-A1 FUNGICIDAL OXIMES AND HYDRAZONES NOX1, QSOX1, XDH CA4 699/4885LTA4H 1057/4885TSHR 4101/4885
US-20140171316-A1 ANTHRANILAMIDE COMPOUNDS AND THEIR USE AS PESTICIDES ANTXR2, NQO2, AAAS CA4 298/4885LTA4H 1075/4885TSHR 3329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.