Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | PPIB | P23284 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | PPID | Q08752 | 1/20 | 0.35 |
| ▸ | PPIG | Q13427 | 1/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14659905 | 0.85 | CYP2C19 (0.44) | CYP1A2CYP3A4LMNAMAOAPDE4D | |
| SCHEMBL14668358 | 0.80 | CYP2C19 (0.59) | CYP1A2LMNAALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL2476201 | 0.77 | MAPK1 (0.48) | CYP1A2CYP3A4LMNAMAOAALDH1A1 | |
| SCHEMBL25512278 | 0.77 | LMNA (0.44) | LMNAALDH1A1MEN1KMT2AMMP8 | |
| SCHEMBL14668353 | 0.75 | TSHR (0.37) | CYP1A2CYP3A4LMNAMAOAALDH1A1 | |
| SCHEMBL11681491 | 0.73 | RAB9A (0.44) | LMNAALDH1A1KMT2AMMP8MAPK1 | |
| SCHEMBL17403411 | 0.71 | RAB9A (0.42) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL14595285 | 0.71 | CNR2 (0.42) | CYP1A2CYP3A4LMNAMAOAALDH1A1 | |
| SCHEMBL7627615 | 0.71 | CYP2C19 (0.48) | LMNAALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL15997340 | 0.70 | CYP2C19 (0.37) | KMT2ATSHRSMN1; SMN2KDM4ECYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130029961-A1 | Substituted Heterocyclic Aza Compounds | GRUENENTHAL GMBH (DE) | 2013-01-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130029961-A1 | Substituted Heterocyclic Aza Compounds | TRPV1, GPR17, TRPV2 | CYP1A2 1065/4885CYP3A4 673/4885LMNA 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.