SCHEMBL14670243

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL19529533	0.84	TSHR (0.39)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL19530286	0.83	CHRM1 (0.43)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL15346515	0.78	CYP2D6 (0.38)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL14670248	0.78	RNPEP (0.40)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL4578586	0.78	CA2 (0.39)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL17469430	0.78	CHRM1 (0.35)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL2035661	0.78	CHRM1 (0.35)	TSHRCYP2D6CYP2C9CYP2C19CA2
	Hydrochloric Acid SCHEMBL28492070	0.76	CHRM1 (0.33)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL7638052	0.76	CHRM1 (0.33)	TSHRCYP2D6CYP2C9CYP2C19CA2
	SCHEMBL15350742	0.76	THRB (0.38)	TSHRCYP2D6CYP2C9CYP2C19CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.