SCHEMBL14672755

SCHEMBL14672755

CCC(=O)NCc1cc(OC)cc(OC)c1

nearest known ligand 0.71

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TACR1 P25103 1/20 0.60
▸ KMT2A Q03164 3/20 0.59
▸ POLB P06746 1/20 0.59
▸ MEN1 O00255 2/20 0.53
▸ ALDH1A1 P00352 1/20 0.53
▸ HTT P42858 1/20 0.53
▸ SMN1; SMN2 Q16637 1/20 0.53
▸ MTNR1A P48039 1/20 0.52
▸ MTNR1B P49286 1/20 0.52
▸ EPHX2 P34913 2/20 0.50
▸ CYP3A4 P08684 1/20 0.49
▸ CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6289037 0.86 TACR1 (0.60) TACR1KMT2APOLBMEN1ALDH1A1
SCHEMBL6289038 0.86 TACR1 (0.60) TACR1KMT2APOLBMEN1ALDH1A1
SCHEMBL934348 0.83 ALDH1A1 (0.76) POLBALDH1A1HTTSMN1; SMN2MTNR1A
SCHEMBL933858 0.82 NPC1 (0.67) KMT2APOLBMEN1ALDH1A1
SCHEMBL5670829 0.81 TACR1 (0.55) TACR1KMT2AMEN1ALDH1A1HTT
SCHEMBL2341547 0.81 TACR1 (0.59) TACR1KMT2APOLBMEN1ALDH1A1
SCHEMBL5340479 0.80 TACR1 (0.54) TACR1KMT2AMEN1ALDH1A1HTT
SCHEMBL13306937 0.79 TACR1 (0.52) TACR1KMT2APOLBMEN1ALDH1A1
SCHEMBL8146896 0.78 MTNR1B (0.67) ALDH1A1HTTSMN1; SMN2MTNR1AMTNR1B
SCHEMBL14521466 0.77 KMT2A (0.57) TACR1KMT2AMEN1ALDH1A1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8809280-B2 Therapeutic peptides LYTIX BIOPHARMA AS (NO) 2014-08-19 — — US disclosed
US-20130035296-A1 THERAPEUTIC PEPTIDES LYTIX BIOPHARMA AS (NO) 2013-02-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130035296-A1 THERAPEUTIC PEPTIDES VIP, LNPEP, ANPEP TACR1 1367/4885KMT2A 4343/4885POLB 1830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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