SCHEMBL14675162

SCHEMBL14675162

CCC(O)CCCCCCCCCCCCCCCC=CCC1=NCCN1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 1/20 0.34
FFAR4 Q5NUL3 1/20 0.34
HTR1D P28221 3/20 0.33
NISCH Q9Y2I1 5/20 0.31
MAOA P21397 3/20 0.31
MAOB P27338 3/20 0.31
TAAR1 Q96RJ0 2/20 0.31
HTR1B P28222 1/20 0.31
FAAH O00519 1/20 0.30
ADRA1A P35348 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14675201 1.00 FFAR1 (0.34) FFAR1FFAR4HTR1DNISCHMAOA
SCHEMBL355032 0.86 ALDH1A1 (0.38) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL14673843 0.86 ALDH1A1 (0.38) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL11560688 0.82 HTR1D (0.44) HTR1DTAAR1FAAH
SCHEMBL16855 0.82 HTR1D (0.44) HTR1DTAAR1FAAH
SCHEMBL451606 0.81 NISCH (0.35) HTR1DNISCHMAOAMAOBTAAR1
Acetic Acid SCHEMBL7721611 0.78 MAOA (0.33) HTR1DNISCHMAOAMAOBTAAR1
SCHEMBL4968225 0.75 HTR1D (0.43) FFAR1FFAR4HTR1DNISCHMAOA
Acetic Acid SCHEMBL16993475 0.74 SLC6A5 (0.34) NISCHMAOAMAOBTAAR1ADRA1A
SCHEMBL6673295 0.72 FFAR1 (0.40) FFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944844-B2 Constraining pyrite activity in shale SMART CHEMICAL SERVICES, LP (US) 2018-04-17 US disclosed
US-20160251569-A1 Constraining Pyrite Activity in Shale AMARILLO NATIONAL BANK 2016-09-01 US disclosed
US-9309453-B2 Constraining pyrite activity in shale SMART CHEMICAL SERVICES, LP (US) 2016-04-12 US disclosed
US-8895482-B2 Constraining pyrite activity in shale SMART CHEMICAL SERVICES, LP (US) 2014-11-25 US disclosed
US-20130284427-A1 Constraining Pyrite Activity in Shale SMART CHEMICAL SERVICES, LP (US) 2013-10-31 US disclosed
US-20130035264-A1 Constraining Pyrite Activity in Shale AMARILLO NATIONAL BANK 2013-02-07 US disclosed