Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | DRD2 | P14416 | 3/20 | 0.70 |
| ▸ | DRD3 | P35462 | 3/20 | 0.70 |
| ▸ | PHF13 | Q86YI8 | 1/20 | 0.64 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CCR2 | P41597 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481939 | 0.89 | TSHR (0.66) | TSHRDRD2DRD3PHF13L3MBTL3 | |
| SCHEMBL2493968 | 0.88 | ALDH1A1 (0.71) | TSHRDRD2DRD3L3MBTL1CYP1A2 | |
| SCHEMBL13211890 | 0.86 | NPSR1 (0.77) | DRD2DRD3L3MBTL1CYP1A2CYP2D6 | |
| SCHEMBL2555571 | 0.86 | CCR3 (0.67) | DRD2DRD3CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14679113 | 0.84 | NPSR1 (0.79) | DRD2DRD3L3MBTL3L3MBTL1CYP1A2 | |
| SCHEMBL4910001 | 0.84 | DRD2 (0.67) | TSHRDRD2DRD3DRD4MAPT | |
| SCHEMBL17194365 | 0.84 | L3MBTL3 (0.72) | TSHRDRD2DRD3L3MBTL3L3MBTL1 | |
| SCHEMBL13211930 | 0.82 | NPSR1 (0.79) | L3MBTL3L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL5474202 | 0.81 | ALDH1A1 (0.71) | DRD2L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL14006065 | 0.81 | HTR3A (0.73) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | SIENA BIOTECH S.P.A. (IT) | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080275028-A1 | Modulators or Alpha7 Nicotinic Acetylcholine Receptors and Therapeutic Uses Thereof | CHRNA7, CHRNA5, CHRNA1 | TSHR 521/4885DRD2 582/4885DRD3 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.