SCHEMBL14680481

SCHEMBL14680481

CC(C)(C)c1cc2cc(C(C)(C)C)cc3c4ccc(-c5cc6cc(-c7ccc8c9cc(C(C)(C)C)cc%10cc(C(C)(C)C)cc(c%11cccc7c%118)c%109)c(O)cc6cc5O)c5cccc(c(c1)c23)c54

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.33
HDAC2 Q92769 1/20 0.33
HDAC8 Q9BY41 1/20 0.33
PPARG P37231 1/20 0.32
RCE1 Q9Y256 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HPGD P15428 1/20 0.31
ALOX15 P16050 1/20 0.31
HSD17B10 Q99714 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
TRPM4 Q8TD43 1/20 0.31
HSP90AA1 P07900 1/20 0.30
HSP90AB1 P08238 1/20 0.30
GABRA1 P14867 1/20 0.30
GABRB2 P47870 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2448831 0.83 CYP1A2 (0.44) PPARGRCE1ALDH1A1HPGDHSD17B10
SCHEMBL2453098 0.80 ALDH1A1 (0.37) RCE1ALDH1A1HPGDHSD17B10
SCHEMBL2453096 0.78 CYP1A2 (0.38) RCE1ALDH1A1HPGDHSD17B10HSP90AA1
SCHEMBL7528069 0.77
SCHEMBL22534075 0.77 ALDH1A1 (0.41) HDAC4HDAC2HDAC8RCE1ALDH1A1
SCHEMBL29818226 0.77 ALDH1A1 (0.41) HDAC4HDAC2HDAC8RCE1ALDH1A1
SCHEMBL515458 0.77 ALDH1A1 (0.41) HDAC4HDAC2HDAC8RCE1ALDH1A1
SCHEMBL14682169 0.75
SCHEMBL133411 0.75 CYP1A2 (0.39) HDAC4HDAC2HDAC8RCE1ALDH1A1
SCHEMBL925882 0.73 CYP1A2 (0.42) HDAC4HDAC2HDAC8RCE1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-8963813-B2 Organic compound and organic light emitting device having the same CANON KABUSHIKI KAISHA (JP) 2015-02-24 US disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130033416-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE HAVING THE SAME TRPA1, OCIAD1, BMP2 HDAC4 3410/4885HDAC2 2443/4885HDAC8 2839/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.