Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | RARB | P10826 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680959 | 0.83 | CNR1 (0.51) | CYP3A4CYP2D6TDP1TLR8LMNA | |
| Water SCHEMBL28833009 | 0.82 | TYR (0.43) | CYP3A4RARBMAPTTSHRTDP1 | |
| Methyl Alcohol SCHEMBL27900235 | 0.80 | TYR (0.46) | CYP3A4RARBMAPTTSHRTDP1 | |
| SCHEMBL24115201 | 0.78 | TDP1 (0.46) | CYP3A4CYP2D6MAPTTSHRTDP1 | |
| SCHEMBL14680982 | 0.77 | CYP1A2 (0.47) | CYP2D6GPR3LIPG | |
| Bromide SCHEMBL30074237 | 0.76 | CYP3A4 (0.49) | CYP3A4CYP2D6RARBMAPTTSHR | |
| SCHEMBL10429729 | 0.76 | LIPG (0.45) | RARBGPR3LIPG | |
| Hydrogen Sulfide SCHEMBL3280224 | 0.76 | TYR (0.42) | CYP3A4RARBMAPTTSHRTDP1 | |
| SCHEMBL19854385 | 0.75 | TP53 (0.54) | CYP3A4MAPTTSHRTDP1MEN1 | |
| SCHEMBL19854457 | 0.75 | TP53 (0.54) | CYP3A4MAPTTSHRTDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796461-B2 | 1,2,4,5-substituted phenyl compound, method for producing same and organic electroluminescent device comprising same as constituent | TOSOH CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | TOSOH CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | XDH, OR10J3, HAX1 | CYP3A4 323/4885CYP2D6 992/4885RARB 4689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.