Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | KIF11 | P52732 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.44 |
| ▸ | GAK | O14976 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14680777 | 0.78 | CYP2A6 (0.56) | KDM4EKIF11SMN1; SMN2CYP3A4CYP2D6 | |
| SCHEMBL13907344 | 0.77 | MAPT (0.73) | MAPTLMNAKDM4EKIF11SMN1; SMN2 | |
| SCHEMBL29733664 | 0.76 | KDM4E (0.71) | MAPTLMNAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL4094356 | 0.76 | KDM4E (0.71) | MAPTLMNAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL27993637 | 0.75 | PDGFRB (0.50) | MAPTLMNAKDM4EUSP2SMN1; SMN2 | |
| SCHEMBL10000032 | 0.74 | MAPT (0.92) | MAPTLMNAKDM4EKIF11SMN1; SMN2 | |
| SCHEMBL135626 | 0.74 | MAPT (0.92) | MAPTLMNAKDM4EKIF11SMN1; SMN2 | |
| SCHEMBL14680953 | 0.73 | MAPT (0.58) | MAPTLMNAKDM4EUSP2KIF11 | |
| SCHEMBL15669200 | 0.73 | GAK (0.50) | MAPTKDM4ESMN1; SMN2PDGFRBPDGFRA | |
| SCHEMBL12198319 | 0.72 | CYP17A1 (0.49) | MAPTLMNAKDM4EUSP2PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8796461-B2 | 1,2,4,5-substituted phenyl compound, method for producing same and organic electroluminescent device comprising same as constituent | TOSOH CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-8796461-B2 | 1,2,4,5-substituted phenyl compound, method for producing same and organic electroluminescent device comprising same as constituent | TOSOH CORPORATION (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | TOSOH CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | TOSOH CORPORATION (JP) | 2013-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130035491-A1 | 1,2,4, 5-SUBSTITUTED PHENYL COMPOUND, METHOD FOR PRODUCING SAME AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME AS CONSTITUENT | XDH, OR10J3, HAX1 | MAPT 3734/4885LMNA 1893/4885KDM4E 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.