Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733664 | 1.00 | KDM4E (0.71) | KDM4EUSP2NPC1CYP17A1RAB9A | |
| SCHEMBL29069510 | 0.88 | CYP1A2 (0.81) | KDM4EUSP2NPC1RAB9ACYP3A4 | |
| SCHEMBL14547341 | 0.88 | CYP17A1 (0.71) | KDM4EUSP2NPC1CYP17A1RAB9A | |
| SCHEMBL29069514 | 0.88 | CYP1A2 (0.81) | KDM4EUSP2NPC1RAB9ACYP3A4 | |
| SCHEMBL9099431 | 0.84 | CLK4 (0.61) | KDM4EUSP2NPC1CYP17A1RAB9A | |
| SCHEMBL9099848 | 0.84 | CLK4 (0.61) | KDM4EUSP2NPC1CYP17A1RAB9A | |
| SCHEMBL61315 | 0.84 | — | — | |
| SCHEMBL8213963 | 0.84 | CYP1A2 (0.62) | KDM4EUSP2NPC1CYP17A1RAB9A | |
| SCHEMBL6733562 | 0.84 | CA1 (0.79) | KDM4ENPC1RAB9ACYP3A4SMN1; SMN2 | |
| SCHEMBL197522 | 0.84 | CA1 (0.79) | KDM4ENPC1RAB9ACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136777-A | C4-aryl pyridine iodized salt organic room-temperature phosphorescent material, and preparation method and application thereof | 天津师范大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-119409858-A | Protonated product of pyridine derivative and compound, preparation method and application thereof | 天津师范大学 | 2025-02-11 | — | — | CN | disclosed |
| US-11649253-B2 | Terbium and dysprosium complexes with optimised antenna, used as luminescent markers | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2023-05-16 | — | — | US | disclosed |
| US-20200284946-A1 | ORGANIC OPTICAL MATERIAL | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2020-09-10 | — | — | US | disclosed |
| WO-2020163917-A1 | PHOTOPERIODIC CONTROL OF PHYTOCHROME WITH MATERIALS | Lleaf Pty Ltd (AU) | 2020-08-20 | — | — | WO | disclosed |
| EP-3674381-A1 | ORGANIC OPTICAL MATERIAL | Japan Science and Technology Agency (JP) | 2020-07-01 | — | — | EP | disclosed |
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (US) | 2019-08-06 | — | — | US | disclosed |
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | SANFORD-BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE (US) | 2019-08-06 | — | — | US | disclosed |
| WO-2019028508-A1 | \"COMPOUNDS AS POTENTIAL DYE MOLECULES\ | Lleaf Pty Ltd (AU) | 2019-02-14 | — | — | WO | disclosed |
| US-20190010126-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | Sanford Burnham Prebys Medical Discovery Institute | 2019-01-10 | — | — | US | disclosed |
| US-6071928-A | Spiro-piperidine derivatives and their use as therapeutic agents | MERCK SHARP & DOHME, LTD. (GB) | 2000-06-06 | — | — | US | disclosed |
| US-6060469-A | Spiro-piperidine derivatives and their use as tachykinin antagonists | MERCK SHARP & DOHME LTD. (GB) | 2000-05-09 | — | — | US | disclosed |
| EP-0885193-A1 | TRIARYL COMPOUNDS | Novartis AG (CH) | 1998-12-23 | — | — | EP | disclosed |
| WO-1997032853-A1 | TRIARYL COMPOUNDS | NOVARTIS AG (CH) | 1997-09-12 | — | — | WO | disclosed |
| WO-1997019084-A1 | SPIRO-PIPERIDINE DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1997-05-29 | — | — | WO | disclosed |
| EP-0711290-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |
| EP-0290591-B1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK PATENT GmbH (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0290591-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS. | MERCK PATENT GMBH (DE) | 1988-11-17 | — | — | EP | disclosed |
| WO-1988004305-A1 | MATERIALS WITH NITROGENOUS SIX-MEMBERED RINGS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1988-06-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10370333-B2 | Sulfonamide compounds and uses as TNAP inhibitors | TNNI3, TNKS1BP1, TNNT2 | KDM4E 1357/4885USP2 1127/4885NPC1 3892/4885 |
| US-20200284946-A1 | ORGANIC OPTICAL MATERIAL | SLC43A1, SLCO4C1, SLCO1A2 | KDM4E 3282/4885USP2 4714/4885NPC1 68/4885 |
| US-20190010126-A1 | SULFONAMIDE COMPOUNDS AND USES AS TNAP INHIBITORS | TNNI3, TNKS1BP1, TNNT2 | KDM4E 1357/4885USP2 1127/4885NPC1 3892/4885 |
| US-11649253-B2 | Terbium and dysprosium complexes with optimised antenna, used as luminescent markers | SSB, TACR3, MAL2 | KDM4E 4758/4885USP2 4657/4885NPC1 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.