Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.45 |
| ▸ | CHRNG | P07510 | 1/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.45 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.45 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.45 |
| ▸ | CHRND | Q07001 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14683141 | 0.99 | NPC1 (0.48) | KCNQ2HTTNPC1RAB9AMEN1 | |
| SCHEMBL14683138 | 0.90 | L3MBTL1 (0.53) | HTTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL14683135 | 0.89 | POLB (0.55) | KCNQ2MEN1KMT2APOLBROCK2 | |
| SCHEMBL14683120 | 0.84 | POLB (0.47) | KCNQ2NPC1RAB9ASLC6A2SLC6A3 | |
| SCHEMBL14683337 | 0.82 | RECQL (0.52) | KCNQ2RAB9AMEN1KMT2ASLC6A2 | |
| SCHEMBL14683131 | 0.82 | LMNA (0.41) | KMT2ASLC6A2SLC6A3GAASLC6A4 | |
| SCHEMBL14683336 | 0.82 | HPGD (0.48) | KCNQ2NPC1RAB9ASLC6A2SLC6A3 | |
| SCHEMBL14683143 | 0.81 | RECQL (0.51) | KCNQ2RAB9AMEN1KMT2ASLC6A2 | |
| SCHEMBL14683127 | 0.81 | TSHR (0.40) | HTTKMT2ASLC6A2SLC6A3CHRNA1 | |
| SCHEMBL2176161 | 0.80 | L3MBTL1 (0.50) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2617706-B1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD (CN) | 2017-09-06 | — | — | EP | claimed |
| US-9556107-B2 | Intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2017-01-31 | — | — | US | claimed |
| US-20160052866-A1 | Novel Intermediate Used for Preparing Tapentadol or Analogues Thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2016-02-25 | — | — | US | claimed |
| US-8853393-B2 | Intermediate for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2014-10-07 | — | — | US | claimed |
| US-20130231478-A1 | Novel Intermediate for Preparing Tapentadol or Analogues Thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2013-09-05 | — | — | US | claimed |
| EP-2617706-A1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | Anhui New Star Pharmaceutical Development Co., Ltd (CN) | 2013-07-24 | — | — | EP | claimed |
| EP-2617706-B1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD (CN) | 2017-09-06 | — | — | EP | disclosed |
| EP-2617706-B1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | ANHUI NEW STAR PHARMACEUTICAL DEV CO LTD (CN) | 2017-09-06 | — | — | EP | disclosed |
| US-9682918-B2 | intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVLOPMENT CO., LTD. (CN) | 2017-06-20 | — | — | US | disclosed |
| US-9682918-B2 | intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVLOPMENT CO., LTD. (CN) | 2017-06-20 | — | — | US | disclosed |
| US-9682918-B2 | intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVLOPMENT CO., LTD. (CN) | 2017-06-20 | — | — | US | disclosed |
| US-9556107-B2 | Intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2017-01-31 | — | — | US | disclosed |
| US-9556107-B2 | Intermediate used for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2017-01-31 | — | — | US | disclosed |
| US-8853393-B2 | Intermediate for preparing tapentadol or analogues thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2014-10-07 | — | — | US | disclosed |
| US-20130231478-A1 | Novel Intermediate for Preparing Tapentadol or Analogues Thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2013-09-05 | — | — | US | disclosed |
| US-20130231478-A1 | Novel Intermediate for Preparing Tapentadol or Analogues Thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2013-09-05 | — | — | US | disclosed |
| US-20130231478-A1 | Novel Intermediate for Preparing Tapentadol or Analogues Thereof | ANHUI NEW STAR PHARMACEUTICAL DEVELOPMENT CO., LTD. (CN) | 2013-09-05 | — | — | US | disclosed |
| EP-2617706-A1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | Anhui New Star Pharmaceutical Development Co., Ltd (CN) | 2013-07-24 | — | — | EP | disclosed |
| EP-2617706-A1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | Anhui New Star Pharmaceutical Development Co., Ltd (CN) | 2013-07-24 | — | — | EP | disclosed |
| WO-2013016840-A1 | NOVEL INTERMEDIATE USED FOR PREPARING TAPENTADOL OR ANALOGUES THEREOF | 安徽省新星药物开发有限责任公司 (CN) | 2013-02-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231478-A1 | Novel Intermediate for Preparing Tapentadol or Analogues Thereof | CYP1A2, CYP7A1, CYP3A5 | KCNQ2 887/4885HTT 2046/4885NPC1 1953/4885 |
| US-20160052866-A1 | Novel Intermediate Used for Preparing Tapentadol or Analogues Thereof | CYP1A2, CYP7A1, ACHE | KCNQ2 919/4885HTT 2006/4885NPC1 2160/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.