Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.59 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | F10 | P00742 | 9/20 | 0.57 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.57 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.57 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 12/20 | 0.48 |
| ▸ | TMPRSS6 | Q8IU80 | 1/20 | 0.48 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 1/20 | 0.47 |
| ▸ | C1S | P09871 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MASP2 | O00187 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6180083 | 0.90 | F2 (0.54) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL6204477 | 0.90 | F2 (0.54) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL6207335 | 0.81 | PRMT5 (0.61) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL10668598 | 0.79 | PRMT5 (0.64) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| Hydrochloric Acid SCHEMBL10668601 | 0.79 | PRMT5 (0.64) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL6204550 | 0.78 | PRMT5 (0.57) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL5456054 | 0.76 | ALDH1A1 (0.67) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| Bromide SCHEMBL11499076 | 0.75 | PRSS1 (0.57) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 | |
| SCHEMBL8669208 | 0.75 | ALDH1A1 (0.59) | ALDH1A1APEX1 | |
| Hydrochloric Acid SCHEMBL9280078 | 0.75 | PRSS1 (0.57) | PRMT5PRMT1ALDH1A1HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071285-A1 | LOW-MOLECULAR SERINE PROTEASES INHIBITORS COMPRISING POLYHYDROXY-ALKYL AND POLYHYDROXY-CYCLOALKYL RADICALS | ABBOTT GMBH & CO. KG (DE) | 2011-03-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071285-A1 | LOW-MOLECULAR SERINE PROTEASES INHIBITORS COMPRISING POLYHYDROXY-ALKYL AND POLYHYDROXY-CYCLOALKYL RADICALS | F2R, C1R, PRSS1 | PRMT5 2250/4885PRMT1 2004/4885ALDH1A1 2835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.