Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 known ✓ | P27487 | 20/20 | 0.93 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.93 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.91 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.77 |
| ▸ | ACE | P12821 | 1/20 | 0.71 |
| ▸ | HTR2A | P28223 | 1/20 | 0.71 |
| ▸ | FAP | Q12884 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2667453 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| SCHEMBL15024075 | 0.96 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL16227400 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL15768042 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL16227221 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL2388619 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL877068 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL1935052 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL16227169 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE | |
| Sitagliptin SCHEMBL16227491 | 0.87 | DPP4 (1.00) | DPP4DPP8DPP7DPP9ACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471016-B2 | Process for the preparation of chiral beta amino carboxamide derivatives | SUN PHARMACEUTICAL INDUSTRIES LTD. | 2013-06-25 | — | — | US | disclosed |
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | SUN PHARMACEUTICAL INDUSTRIES LTD (IN) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130041150-A1 | PROCESS FOR THE PREPARATION OF CHIRAL BETA AMINO CARBOXAMIDE DERIVATIVES | BCAT2, BCAT1, SUCLA2 | DPP4 885/4885DPP8 1777/4885DPP7 1083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.