Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14687532 | 1.00 | P2RX3 (0.39) | P2RX3KDM4EKMT2ACA1CA2 | |
| SCHEMBL14688193 | 0.82 | ALDH1A1 (0.53) | P2RX3KDM4EKMT2ACA1CA2 | |
| SCHEMBL14688195 | 0.82 | ALDH1A1 (0.53) | P2RX3KDM4EKMT2ACA1CA2 | |
| SCHEMBL14575607 | 0.81 | KDM4E (0.44) | P2RX3KDM4EKMT2AALDH1A1MEN1 | |
| SCHEMBL11016592 | 0.78 | KDM4E (0.50) | KDM4EKMT2ACA1CA2CA4 | |
| SCHEMBL11016590 | 0.78 | KDM4E (0.50) | KDM4EKMT2ACA1CA2CA4 | |
| SCHEMBL11715951 | 0.77 | KDM4E (0.38) | P2RX3KDM4EKMT2ACA1CA2 | |
| SCHEMBL11715941 | 0.77 | KDM4E (0.38) | P2RX3KDM4EKMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL11014836 | 0.76 | TRIM24 (0.39) | P2RX3KDM4EKMT2ACA1CA2 | |
| Hydrochloric Acid SCHEMBL11014837 | 0.76 | TRIM24 (0.39) | P2RX3KDM4EKMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | claimed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | claimed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | P2RX3, P2RX1, P2RX2 | P2RX3 1/4885KDM4E 3029/4885KMT2A 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.