Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.53 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.44 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14688195 | 1.00 | ALDH1A1 (0.53) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL14687531 | 0.82 | P2RX3 (0.39) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL14687532 | 0.82 | P2RX3 (0.39) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL11016592 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL11016590 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL11715941 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL11715951 | 0.78 | KDM4E (0.38) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| SCHEMBL11011837 | 0.77 | KDM4E (0.57) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL11014836 | 0.77 | TRIM24 (0.39) | ALDH1A1KDM4EKMT2ALMNAHPGD | |
| Hydrochloric Acid SCHEMBL11014837 | 0.77 | TRIM24 (0.39) | ALDH1A1KDM4EKMT2ALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | claimed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | claimed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-9546139-B2 | Pyridine carboxylic acid based compound used as a P2X1 and P2X3 receptor antagonist, a production method for the same and a composition comprising the same | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2017-01-17 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2013-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130040997-A1 | NOVEL PYRIDINE CARBOXYLIC ACID BASED COMPOUND USED AS A P2X1 AND P2X3 RECEPTOR ANTAGONIST, A PRODUCTION METHOD FOR THE SAME AND A COMPOSITION COMPRISING THE SAME | P2RX3, P2RX1, P2RX2 | ALDH1A1 619/4885KDM4E 3029/4885KMT2A 3142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.