Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.34 |
| ▸ | HTR1A | P08908 | 3/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788522 | 0.81 | GABRA1 (0.41) | GABRA1GABRB2C5AR1ADRA2BADRA2C | |
| SCHEMBL8614499 | 0.78 | GABRA1 (0.39) | GABRA1GABRB2C5AR1ADRA2BADRA2C | |
| SCHEMBL84249 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2C5AR1ADRA2BADRA2C | |
| SCHEMBL8519275 | 0.76 | KEAP1 (0.40) | ALDH1A1HTTKDM4E | |
| SCHEMBL7302336 | 0.76 | C5AR1 (0.35) | C5AR1ALDH1A1LMNAHTT | |
| SCHEMBL2586271 | 0.75 | GABRA1 (0.47) | GABRA1GABRB2ADRA2BADRA2CADRA2A | |
| SCHEMBL8755334 | 0.75 | GABRA1 (0.42) | GABRA1GABRB2ADRA2BADRA2CADRA2A | |
| Hydrochloric Acid SCHEMBL29044792 | 0.73 | GABRA1 (0.41) | GABRA1GABRB2ADRA2BADRA2CADRA2A | |
| SCHEMBL5490438 | 0.73 | KMT2A (0.41) | C5AR1ALDH1A1LMNAHTTKDM4E | |
| SCHEMBL9274584 | 0.73 | TSHR (0.40) | GABRA1GABRB2C5AR1ADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | BAYER CROPSCIENCE AG | 2011-03-24 | — | — | US | disclosed |
| US-20040102635-A1 | Novel tetrazolinone derivatives | YANAGI AKIHIKO (JP) | 2004-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110071141-A1 | Pesticidial Condensed-Ring Aryl Compounds | DDT, PRDX4, CYP4X1 | GABRA1 2024/4885GABRB2 1790/4885C5AR1 1171/4885 |
| US-20040102635-A1 | Novel tetrazolinone derivatives | CBR1, CBR3, CYP1B1 | GABRA1 1837/4885GABRB2 2192/4885C5AR1 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.